- A Case of Successful Treatment of Hepatocellular Carcinoma with a Pulmonary Metastasis by Combining Pulmonary Wedge Resection and Sorafenib
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Sun Jae Lee, Hyung Joon Yim, Hwan Hoon Chung, Hae Rim Kim, Eileen L. Yoon, Jong Jin Hyun, Sung Woo Jung, Ja Seol Koo, Rok Son Choung, Sang Woo Lee, Jai Hyun Choi
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Journal of the Korean Liver Cancer Study Group. 2012;12(1):67-70. Published online February 28, 2012
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Abstract
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- 35-year-old female patient was diagnosed with hepatocellular carcinoma and underwent hepatic resection. 12 months after
hepatic resection, serum AFP rose (119.6 ng/mL) but no definite recurrence was found on imaging modalities. 30 months after
hepatic resection, serum AFP rose up to 1008.5 ng/mL and metastatic nodule was found in right lower lung in chest CT. Video
assisted thoracoscopic wedge resection was performed and 400 mg/day of sorafenib was intiated. Serum AFP returned to normal
range after 2 months of pulmonary resection. No evidence of recurrence is noted after 30 months of pulmonary resection. We
think that pulmonary resection plus sorafenib combination therapy resulted in favorable treatment outcome in this patient.
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